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Plasma Fillers

Alternative To Synthetic Fillers

Smart Cell Plasma Filler is an advanced autologous treatment, utilising the patient's own plasma for the stimulation and acceleration of tissue healing and regeneration.​ It is a versatile system that allows the practitioner to formulate variable consistencies to adapt to the characteristics of each application with excellent cell bio-compatibility and safety profile.

This novel autologous filler, is composed of the patient’s plasma, which is prepared from the patient’s own blood. It provides an immediate filler effect because of its gel-like consistency. Not only does the Plasma Filler improve volume loss, it safely boosts fibroblast expansion and is viewed as an effective treatment to avoid adverse reactions based on infusion-induced complications . 

A Biological Supplement


Plasma is derived when all the blood cells—red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes)—are separated from whole blood.


Plasma Filler is rich in fibrinogen, a precursor to fibrin which binds to platelets and hyaluronic acid. Hyaluronic acid stimulates fibroblasts.

The three-dimensional matrix serves as a template or scaffold and massively traps the platelets, growth factors, leukocytes, cytokines, and mesenchymal stem cells during the remodelling of tissue.

The PPP serves in its own right as a healing agent which speeds up the healing of wounds and regenerates the target tissue.

As a so-called “fibrin sealant,” PPP is currently utilized in orthopaedic surgery, blood management, and cosmetic surgery.

Plasma Filler Training
Plasma Fillers

What is Autologous

Autologous. [ ô-tŏl ′ə-gəs ] "Derived or transplanted from the same individual's body."

Autologous plasma therapy is natural treatment which taps into the regenerative potential of our body in order to induce tissue repair and regeneration.

Plasma Filler utilises platelet poor plasma (PPP) for the use in tissue engineering as it offers an autologous degradable scaffold.


Although PPP has a low number of platelets (< 10 X 103/μL), it contains elevated levels of fibrinogen, a precursor of fibrin. i-PRF contains concentrated levels of activated platelets which is why i-PRF must be used in conjunction with Plasma Filler.

Fibrin binds to hyaluronic acid which stimulates human fibroblast proliferation within a collagen matrix.


Smart Cell Plasma Filler offers cellular rejuvenation and can be used to:

  • Add volume and smooth out creases

  • Improve fine lines and wrinkles

  • Rejuvenate peri-oral area

  • Treat décolletage

  • Plump recessed scars

  • Enhance contours such as cheeks

  • Improve laxity

  • Treat tear troughs and dark circles

  • Improve tone and texture

  • Certain body areas

A course of 2-3 treatments are recommended, results are immediately visible. Results can last up to 12 months, depending on the thickness of the filler injected and skin condition.

Prolong and improve results with regular i-PRF microneedling treatments.

Plasma fillers
Plasma Fillers

Mode of Action

The Plasma Filler is produced by processing the patient’s own plasma, denaturing the plasma protein by heat, and then combining the obtained gel with iPRF which contains a high concentration of platelets, growth factors and leukocytes.


Plasma Gel has the same colour and consistency as autologous fat, but when injected, the softness is much better than autologous fat and it allows to be more precise and refined.

Plasma Filler Training

Perioral plasma filler

We welcome medical professionals and aesthetic practitioners onto the course.

Learn how to volumise and contour the face with this advanced autologous filler.

Pre-requisite: 6 months injectable experience and competent in phlebotomy. Preferably trained in i-PRF (to offer the full protocol).

Advantages of autologous Plasma Filler:

  • Excellent safety profile

  • A natural alternative to Hyaluronic Acid dermal fillers and other synthetic fillers

  • Offering clients a choice who are nervous or allergic to synthetic fillers

  • Bio-compatible 

  • Stimulates fibroblasts

  • Increases dermal collagen and elastin

  • Tissue regeneration

  • Wound healing benefits

  • Non-invasive

  • Powerful regenerative properties

  • Tailor the consistency of the gel to the indication

  • Dissolves smoothly over time